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Thursday, 14 January 2016

Urine Test to Predicts Alzheimer's -

Urine Test to Predicts Alzheimer's - 

A simple urine test may one day predict the onset of Alzheimer's disease, a devastating condition that affects 5.1 million Americans over the age of 65.

Researchers for the study, which was published by Scientific Reports, observed mice who were given chemical treatment meant to mimic the abnormal brain activity of people with Alzheimer's.

These mice had a urine odor distinct from the urine of mice who were not given the chemical.

The difference in odor was detectable even before researchers could identify plaque build-up in the mice's brains, an indicator meant to simulate Alzheimer's symptoms.

This suggests that the odor is due to a genetic change rather than a developmental one, signaling that the disease may be detectable earlier than previously thought.

"While this research is at the proof-of-concept stage, the identification of distinctive odor signatures may someday point the way to human biomarkers to identify Alzheimer's at early stages," said study author Dr. Daniel Wesson, a neuroscientist at the Case Western Reserve University School of Medicine, in a press release.

While there is currently no test to diagnose Alzheimer's disease, presence of an early biomarker could allow physicians to slow the progression of the disease and explore alternative avenues for treatment.


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